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Zyban

 

Zyban

Zyban (bupropion hydrochloride) is not a nicotine replacement product. Approved in 1997, zyban is a pill that reduces nicotine withdrawal symptoms and the urge to smoke. It cuts down on cravings and withdrawal symptoms such as irritability, frustration, anxiety, restlessness and depression. Buproprion was first approved as a prescription antidepressant. When used for smoking cessation, Zyban appears to affect brain chemicals linked with nicotine addiction. Antidepressants work for depressed people by helping them to feel normal; however, they do not make non depressed people feel happier. Therefore, those using Zyban for smoking cessation do not feel extra happy as a result of the drug. Zyban works with the chemicals in the brain (dopamine and norepinephrine) that are linked to nicotine addiction, cravings and withdrawal symptoms.

More on Zyban
 

Zyban is usually taken as one 150-mg tablet in the morning for the first three days. From the fourth day on, one tablet is taken in the morning and another tablet in the evening. Zyban is usually taken for 7 to 12 weeks, or as indicated by a doctor.

Side Effects of Zyban

Common side effects include dry mouth, problems sleeping, shakiness and skin rashes. These side effects usually disappear after a few weeks. Approximately 3 in 1000 people taking Zyban have an allergic reaction severe enough to require medical attention.

Risks of Zyban

Seizures may occur in approximately 1 out of every 1000 people taking Zyban. Those with preexisting seizure conditions, such as epilepsy or anorexia nervosa should not take Zyban. Those taking other medications that contain bupropion hydrochloride should not take Zyban. Women who are pregnant or breast feeding should not take Zyban.

Those who have taken or are currently taking a monoamine oxidase inhibitor (MAOI) should not take Zyban.

Zyban can be used in conjunction with other nicotine replacement products; however, a doctor's supervision is required to ensure that no rise in blood pressure occurs.


The Centers for Disease Control and Prevention offer excellent information about smoking, tobacco use and smoking cessation resources.  Quitnet is an excellent online aid for all aspects of quitting smoking.


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