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Xenical Studies

Many clinical trials have been carried out with Xenical. The FDA reports that over 4,000 obese participants were studied over 7 clinical trials prior to Xenical FDA approval. The research suggests that Xenical can help to promote weight loss
when used in conjunction with increased physical activity and low fat diet. All participants used Xenical in conjunction with a low fat, reduced calorie diet and regular physical exercise.

Xenical Studies

In the study participants who completed one year of treatment:

  • 57% of those taking Xenical lost at least 5% of their original body weight

  • 31% of those taking a placebo lost at least 5% of their original body weight

In one of the seven studies:

  • Those taking Xenical lost an average of 22.7 pounds

  • Those taking a placebo lost an average of 13.4 pounds

The results of these clinical trials led to the following recommendations by the FDA:

  • Xenical only be prescribed to individuals with a BMI of 30 or higher

  • The exception to the above rule are for individuals with a BMI of 27 or higher who have high cholesterol, high blood pressure or diabetes

Research on Xenical has also demonstrated that Xenical can not only promote successful weight loss when combined with diet and exercise, but may also have a small, but positive, effect in decreasing total cholesterol, LDL cholesterol, insulin levels and blood pressure.

It is important to note that those study participants who participated in a 1 year weight maintenance program after completing the 1 year weight loss program regained some of the weight initially lost. This was true of the participants who
continued taking Xenical as well as those taking a placebo.

There are important observations to be made about the clinical studies of Xenical. Firstly, they indicate that Xenical can successfully promote weight loss in obese individuals. Secondly, weight loss can be successfully obtained without taking Xenical. Thirdly, the results underline the importance of low fat, reduced calorie diets and increased physical activity in the long term maintenance of weight loss.


Learn more about xenical and other medications at the FDA's Center for Drug Evaluation and Research website.  Read about xenical diet pills from Roche Pharmaceuticals USA.


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