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Obesity is a national problem. Obesity not only affects ones overall image of themselves but is linked to countless other health issues such, as but not limited to type 2 diabetes, cardiovascular diseases, coronary heart disease, high blood pressure, certain cancers, stroke and even can cause problems for joints such as knees due to undo stress placed on them. Yet for various reasons, some find it near impossible to eliminate excess body fat even with diet and exercise. Some argue they are not trying hard enough but it is not always that simple, there are certain physiological issues that can literally make it seemingly impossible for one to lose weight. Well there maybe a new medication on the horizon called ContraveŽ.
Contrave is currently an experimental drug for the treatment of obesity. It works by stimulating the hypothalamus part of the brain to control ones appetite. But the ingredients in ContraveŽ have actually been around for some time now. It is a concoction of two medications bupropion SR and Naltrexone SR. Bupropion is an antidepressant as well as a smoking cessation. Naltrexone is used for treatment in alcohol and certain drug additions. But it is the special combination that makes it effective. Bupropion has known to reduce ones weight but is not prescribed as such and if someone comes off this medication their weight tends to go back to normal. This is where the Naltrexone helps out; it helps to carry over that effect for a longer term. It is still unsure if ContraveŽ would be taken for the long term or if it could be taken intermittently but studies have shown it is effective in body weight reduction.
In a scientific study, people taking ContraveŽ lost over 9% of their body weight in a year and some even lost upwards of 15%. And other risks associated with obesity where reduces, things like reduced blood pressure etc. The side effects reported were things like minor constipation and headaches. But unlike other failed obesity medications such as Rimonabant or Taranabant that have been associate with negative psychiatric effects, none where reported with ContraveŽ.
On December 7th a group of doctors that the FDA relies on for recommendations with regards to new drugs voted in favor 13-7 to approve Contrave. This means that on January 31st 2011 the FDA will most likely vote Yes to the approval of Contrave. However the resulting vote turned out negative and Contrave was not approved.
The latest information on Contrave is available here. Also visit the FDA's Center for Drug Evaluation and Research for information about all drugs, including dieting pills. Consult the U.S. Food and Drug Administration's Warnings and Safety Information pages to learn about recent medication alerts, diet supplements alerts and other diet product warnings.
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